Complex structural rearrangement of chromosomes 7, 10, 14 and 21
نویسندگان
چکیده
منابع مشابه
Comparative mapping of human chromosome 10 to pig chromosomes 10 and 14.
Identification of predictive markers in QTL regions that impact production traits in commercial populations of swine is dependent on construction of dense comparative maps with human and mouse genomes. Chromosomal painting in swine suggests that large genomic blocks are conserved between pig and human, while mapping of individual genes reveals that gene order can be quite divergent. High-resolu...
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We describe the characterisation of four alpha satellite sequences which are found on a subset of the human acrocentric chromosomes. Direct sequence study, and analysis of somatic cell hybrids carrying specific human chromosomes indicate a unique 'higher-order structure' for each of the four sequences, suggesting that they belong to different subfamilies of alpha DNA. Under very high stringency...
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Among the F1 larval progeny of an irradiated Drosophila melanogaster male of the Oregon-R stock and an untreated Oregon-R female, there appeared one individual whose salivary-gland chromosomes revealed a complex rearrangement involving at least 32 breaks. The positions of 30 points of breakage were determined; the others remain of uncertain location. Treatment of the father included exposure to...
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complex chromosomal rearrangements (ccrs) are rare events involving more than two chromosomes and over two breakpoints. they are usually associated with infertility or sub fertility in male carriers. here we report a novel case of a ccr in a 30-year-old oligoasthenosperm man with a history of varicocelectomy, normal testes size and normal endocrinology profile referred for chromosome analysis t...
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Five genes on human chromosome 7 (HSA 7) were assigned to bovine chromosome 21 (BTA 21) and 4 (BTA 4) using a bovine-rodent somatic hybrid cell panel. These five genes were alpha-I subunit of adenylate cyclase-inhibiting G-protein (GNAI1), alpha/beta preprotachykinin (TAC1), reelin (RELN), c-AMP dependant protein kinase type II beta regulatory chain (PRKAR2B) and apolipoprotein A1 regulatory pr...
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ژورنال
عنوان ژورنال: Japanese journal of human genetics
سال: 1984
ISSN: 0021-5074
DOI: 10.1007/bf01876503